######################################## Terminologies: SubcellularEntity library ######################################## Related schema specification: `SubcellularEntity `_ ------------ ------------ asymmetricSynapse ----------------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/asymmetricSynapse :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: An 'asymmetric synapse' is characterized by rounded vesicles in the presynaptic cell and a prominent postsynaptic density. Asymmetric synapses are typically excitatory. :name: asymmetric synapse `BACK TO TOP `_ ------------ axon ---- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/axon :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: An 'axon' is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals which are the site of storage and release of neurotransmitter (Gene Ontology). :interlexIdentifier: http://uri.interlex.org/base/ilx_0101043 :name: axon :preferredOntologyIdentifier: http://uri.neuinfo.org/nif/nifstd/sao1770195789 `BACK TO TOP `_ ------------ axonTerminal ------------ .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/axonTerminal :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: The distal terminations of axons which are specialized for the release of neurotransmitters. :description: Also included are varicosities along the course of axons which have similar specializations and also release transmitters. Presynaptic terminals in both the central and peripheral nervous systems are included (MSH). :interlexIdentifier: http://uri.interlex.org/base/ilx_0101049 :knowledgeSpaceLink: https://knowledge-space.org/wiki/GO:0043679#axon-terminus :name: axon terminal :preferredOntologyIdentifier: http://uri.neuinfo.org/nif/nifstd/sao2007137787 `BACK TO TOP `_ ------------ dendrite -------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/dendrite :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A 'dendrite' is a branching protoplasmic process of a neuron that receives and integrates signals coming from axons of other neurons, and conveys the resulting signal to the body of the cell (Gene Ontology). :interlexIdentifier: http://uri.interlex.org/base/ilx_0103021 :name: dendrite :preferredOntologyIdentifier: http://uri.neuinfo.org/nif/nifstd/sao1211023249 `BACK TO TOP `_ ------------ dendriticSpine -------------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/dendriticSpine :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A 'dendritic spine' is a protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. :interlexIdentifier: http://uri.interlex.org/base/ilx_0103030 :name: dendritic spine :preferredOntologyIdentifier: http://uri.neuinfo.org/nif/nifstd/sao1799103720 `BACK TO TOP `_ ------------ mitochondrion ------------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/mitochondrion :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A 'mitochondrion' is a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration (Gene Ontology). :interlexIdentifier: http://uri.interlex.org/base/ilx_0107028 :name: mitochondrion :preferredOntologyIdentifier: http://uri.neuinfo.org/nif/nifstd/sao1860313010 `BACK TO TOP `_ ------------ nerveFiber ---------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/nerveFiber :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A threadlike extension of a nerve cell within the nervous system which consists of an axon and, if myelinated, a myelin sheath. :interlexIdentifier: http://uri.interlex.org/base/ilx_0485634 :knowledgeSpaceLink: https://knowledge-space.org/wiki/UBERON:0006134#nerve-fiber :name: nerve fiber :preferredOntologyIdentifier: http://purl.obolibrary.org/obo/UBERON_0006134 `BACK TO TOP `_ ------------ neurite ------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/neurite :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A 'neurite' is a small neuronal process on developing neurons that ultimately grow out into axons or dendrites under the control of growth stimulating or inhibiting factors from their direct extracellular environment. :name: neurite `BACK TO TOP `_ ------------ neurofilament ------------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/neurofilament :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A 'neurofilament' is a type of intermediate filament found in the core of neuronal axons. Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter. :interlexIdentifier: http://uri.interlex.org/base/ilx_0107475 :name: neurofilament :preferredOntologyIdentifier: http://uri.neuinfo.org/nif/nifstd/sao1316272517 `BACK TO TOP `_ ------------ nucleus ------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/nucleus :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A 'nucleus' is a membrane-bounded organelle of eukaryotic cells that contains the chromosomes. It is the primary site of DNA replication and RNA synthesis in the cell (Gene Ontology) :interlexIdentifier: http://uri.interlex.org/base/ilx_0107735 :name: nucleus :preferredOntologyIdentifier: http://uri.neuinfo.org/nif/nifstd/sao1702920020 `BACK TO TOP `_ ------------ symmetricSynapse ---------------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/symmetricSynapse :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A 'symmetric synapse' has flattened or elongated vesicles, and does not contain a prominent postsynaptic density. Symmetric synapses are typically inhibitory. :name: symmetric synapse `BACK TO TOP `_ ------------ synapticBouton -------------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/synapticBouton :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A 'synaptic bouton' is a terminal pre-synaptic ending of an axon or axon collateral. :interlexIdentifier: http://uri.interlex.org/base/ilx_0111400 :name: synaptic bouton :preferredOntologyIdentifier: http://uri.neuinfo.org/nif/nifstd/sao187426937 `BACK TO TOP `_ ------------ synapticProtein --------------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/synapticProtein :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A 'synaptic protein' belongs to a family of neuron-specific phosphoric proteins associated with synaptic vesicles. Synaptic proteins are present on the surface of almost all synaptic particles and bind to the cytoskeleton. :interlexIdentifier: http://uri.interlex.org/base/ilx_0111412 :name: synaptic protein :preferredOntologyIdentifier: http://uri.neuinfo.org/nif/nifstd/sao936599761 `BACK TO TOP `_ ------------ synapticVesicle --------------- .. admonition:: metadata sheet :@context: @vocab: :@id: https://openminds.ebrains.eu/instances/subcellularEntity/synapticVesicle :@type: https://openminds.ebrains.eu/controlledTerms/SubcellularEntity :definition: A 'synaptic vesicle' is a secretory organelle (~ 50 nm in diameter) released from the pre-synaptic nerve terminal. It accumulates high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the pre-synaptic plasma membrane (modified from Gene Ontology). :interlexIdentifier: http://uri.interlex.org/base/ilx_0111411 :name: synaptic vesicle :preferredOntologyIdentifier: http://uri.neuinfo.org/nif/nifstd/sao1071221672 `BACK TO TOP `_ ------------